Magazine 15 June 2021

Cystitis and Menstrual Cycle: The Links

  1. Background: How the menstrual cycle works
  2. Menstruation and symptoms of cystitis
  3. Post-menstrual phase = calming of cystitis symptoms
  4. Ovulatory phase and the return of cystitis symptoms
  5. Premenstrual phase: The most challenging phase for cystitis


Dear Friend,

The entire female gender deserves the Nobel Prize for patience..

Our reproductive system is complicated and delicate: every month, we deal with the various consequences of hormonal changes and the menstrual cycle symptoms.

Considering the risk of bacterial cystitis and other bladder problems, the Nobel Prize for patience is also small.


Do you ever find that your cystitis symptoms increase at certain times during your menstrual cycle?

If the answer is yes, you are not alone.

Many friends write to me to ask about the connection between cystitis and the menstrual cycle and strategies to ease the discomfort.

Let’s clarify these aspects together: you will be a black belt against cycle-related cystitis at the end of the article. 😉


Background: How the menstrual cycle works

Do notworry. This is not the usual biology class that teaches you things you’ve known all your life..

To begin our discussion about the four phases of the menstrual cycle, I want you understand what I am about to tell you. This will serve as the guiding rudder of our entire discussion.

Our organism is prepared to produce the egg to be fertilized and eventually become pregnant during the menstrual cycle.

Fertility is regulated by the work of the:

  • Hormones (estrogen and progesterone).
  • Ovaries.
  • Nervous system.


The interaction between these three processes causes us to move from one phase of the cycle to another, and our bodies are more or less positively impacted as a result.

Are we clear?

If you need further clarification, please contact me now by clicking here.

Let’s move on to how the four phases of the menstrual cycle affect bladder symptoms and cystitis.

Menstruation and symptoms of cystitis

During your period, you may notice some discomfort not so much related to your bladder as to irritation of the vaginal mucous membranes.

Irritation can come from:

  • Use of tampons.
  • Use of synthetic tampons.
  • Prolonged contact with the wet surface of the external absorbent.
  • Blood.


If you find yourself in this description, a potential solution is to get cotton tampons or try menstrual cups (designed precisely to avoid irritation and direct contact with blood and the positive impact on the environment).

To soothe persistent discomfort or menstrual pain during this phase, you can rely on our Dimann Flogo: its ingredients alleviate inflammation and pain and offering support to natural immune defenses.

At this stage, you may also notice an increase in urination frequency (the number of times you go to pee).


In the phase before menstruation, the increased level of estrogen hormones led to the so-called water retention (accumulation of fluid in the body).

The level of these hormones is reduced, leading to the expulsion of previously accumulated fluids.


Post-menstrual phase = calming of cystitis symptoms

The Post-Menstrual stage should be a time of respite from cystitis and bladder discomfort..

In fact, during the eight days that make it up, the follicle that contains the new egg to be fertilized grows.

For the follicle to survive and develop, the level of estrogen hormones reaches its maximum.

It is precisely the maximum production of estrogen that guarantees us a moment of well-being. 😊

You need to know that estrogen is the ultimate female feel-good hormone.

They ensure the health of your vagina by promoting:

  1. adequate blood flow to his tissues;
  2. and producing the correct collagen (the protein that guarantees tissue tone).

The result? Healthy, toned vaginal tissues and proper lubrication..

That’s not all: the production of collagen, stimulated by estrogen, also benefits the rest of the tissues of your body (so even the bladder tissues that will be strong and less susceptible to trauma or contamination).

In short, dear friend, the peak in estrogen production can only do us good and have positive implications in lowering the risk of cystitis.

Ovulatory phase and the return of cystitis symptoms

We have arrived at a delicate moment.

The follicle containing the egg becomes mature, and there is a sharp drop in the level of estrogen and progesterone to allow the follicle to rupture and release the egg.

The egg is now ready to be fertilized.

The number of vaginal mucus increases, and, at the same time, it becomes more slippery and alkaline (which means that the vaginal pH increases): this will make it easier to ensure the survival and passage of the sperm to the egg.

So, if the estrogen spike provides your wellness in the previous phase, it is that their abrupt drop will help cystitis symptoms again?

Unfortunately, the answer is yes.

A good level of estrogen is essential to ensure a good defense of the mucous membranes from pathogens.

In addition, during the ovulatory phase, the increase in vaginal pH works to the disadvantage of lactobacilli (the “good” bacteria that defend us from the “bad” ones), causing their quantity to decrease.

In theface of all these changes, the mucous membranes of your vagina will become more fragile and sensitive to foreign stimuli.

There you go. Compromising the ability of your mucous membranes to defend themselves will increase your vulnerability to developing cystitis.

Premenstrual phase: The most difficult phase for cystitis

The mature egg travels to the so-called fallopian tubes where it could be fertilized and then passes into the uterus to allow the fetus to develop.

What if it doesn’t get fertilized?

Maybe I’m repetitive, but again, estrogen and progesterone levels will stay low to prepare us for menstruation.

What is the point of this latest drop in hormone levels?

At the base of the endometrium (the mucous membrane that lines the inner cavity of the uterus), there are cells, mast cells, which release certain inflammatory substances.

The inflammatory substances will allow this inner layer detachment giving rise to menstruation.

Okay Lorenza, but what is the connection between bladder and cystitis?

The release of inflammatory substances will occur in the uterus and throughout the rest of the body.

Oh man!

If you are already carrying around an inflamed bladder from previous cystitis,releasing these inflammatory substances will cause your bladder to burn more.

All bladder symptoms will suddenly come back strong: urgency to pee, pain, sense of weight, and persistent burning.

It’s not over yet!

Hormonal surges also reduce your ability to withstand pain and increase muscle contractions.

What a mess, huh?

To help your bladder stay strong, even in the face of the inevitable phenomena of the premenstrual phase, you can consider support from our Dimann Daily.

Its ingredients give you three very important benefits:

  1. They strengthen the bladder’s natural immune defenses.
  2. They reduce the inflammation present on the mucous membranes of the bladder.
  3. They repair the bladder from damage resulting from the previous cystitis.


Arriving prepared for the most hostile moment for your bladder is essential to avoid falling into the usual mechanisms that can ruin your day.

Dear friend, do you want to go deeper into this topic, understand it better or ask me for advice about your specific case? Ask me anything! Just contact me here.

A hug,


P.S.: If you suffer from recurrent cystitis and are looking for a complete remedy, take a look at our Cystitis Kits.



  • Durante le mestruazioni potresti notare alcuni fastidi collegati all’irritazione delle mucose vaginali;
  • During your period, you may notice an increase in urination frequency.
  • The post-menstrual phase is a time of calm in which we benefit from the peak production of estrogen hormones.
  • During ovulation, the mucous membranes of your vagina will become more fragile and sensitive to foreign stimuli.
  • The pre premenstrual phase is the most critical because of inflammatory substances that affect the bladder mucous membranes.

Did we help?

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